Identification of hot regions in protein-protein interactions by sequential pattern mining
نویسندگان
چکیده
منابع مشابه
Hot regions in protein--protein interactions: the organization and contribution of structurally conserved hot spot residues.
Structurally conserved residues at protein-protein interfaces correlate with the experimental alanine-scanning hot spots. Here, we investigate the organization of these conserved, computational hot spots and their contribution to the stability of protein associations. We find that computational hot spots are not homogeneously distributed along the protein interfaces; rather they are clustered w...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2007
ISSN: 1471-2105
DOI: 10.1186/1471-2105-8-s5-s8